Unexplained loss of muscle mass - Rejuvenate Clinic

What is unexplained loss of muscle mass?

Unexplained loss of muscle mass, also known as idiopathic sarcopenia, is a concerning condition where muscle seems to waste away or atrophy for no clear reason. This leads to feelings of weakness, fatigue, and reduced quality of life.

Some potential causes that doctors investigate include:

• Age-related muscle loss (sarcopenia of aging)
• Poor nutrition or calorie deficit
• Endocrine disorders like low testosterone or thyroid problems
• Side effects of certain medications
• Inflammatory diseases
• Neurological conditions

However, sometimes despite a full medical workup, no cause can be identified. This idiopathic sarcopenia is frustrating for both patients and doctors.

What are the key symptoms?

The main symptom is progressive loss of muscle mass. This leads to:

• Decreased muscle strength
• Impaired mobility
• Difficulty with daily activities
• Greater fatigue and exhaustion

Sometimes weight loss accompanies the muscle loss as body composition shifts.

How is it evaluated and diagnosed?

Doctors use several approaches to evaluate and diagnose unexplained muscle loss:

• Medical history and physical exam focusing on the symptoms
• Blood tests to check hormones, inflammation, etc
• Imaging tests like MRI or muscle biopsies
• Testing muscle strength and function

If no cause is found after a thorough workup, then idiopathic sarcopenia may be diagnosed.

What treatments are available?

Sadly, no highly effective treatments exist for idiopathic muscle wasting:

• Physical therapy and strength training may help slow progression
• Addressing contributing factors like poor nutrition
• Experimental medications being researched

The outlook depends greatly on the severity and underlying cause. Close monitoring by a doctor is important. Research into new treatments offers hope.

Let me know if you have any other questions! I'm happy to discuss this complex topic further.